ePlasty: Vol. 17
Desmoplastic Melanoma
Anthony Maurice Kordahi, MD, Joshua B. Elston, MD, Ellen M. Robertson, MD, and C. Wayne Cruse, MD

Division of Plastic Surgery, Department of Surgery, University of California San Diego; and University of South Florida Morsani College of Medicine, Tampa

Correspondence: kordahi.amk@gmail.com
Keywords: desmoplastic melanoma, skin cancer, spindle cell, neurotropism, desmoplasia
Figure 1.
Figure 2.


A 69-year-old man presented with a 2-year history of a recurrent, nonpigmented, nodular scalp lesion. He underwent surgical excision with scalp flap reconstruction. The lesion was analyzed 3 times for pathologic diagnosis; however, none of the prior specimens had undergone immunostaining. He was subsequently diagnosed with mixed desmoplastic melanoma, at least 6.84 mm in depth.


1. What is desmoplastic melanoma (DM)?

2. What are some of the proteins involved in DM expression and diagnosis?

3. What is the preferred  .......