ePlasty: Vol. 11
Influence of Receptor Antagonists, Local Anesthetics, and Denervation on Microcirculation
Heinz H. Homann, MD,a Tobias Hirsch, MD,b H.U. Steinau,b Thomas Muehlberger, MD,c Wibke Moll, MD,b Marcus Lehnhardt, MD,d and Ole Goertz, MDb

aDepartment of Plastic, Reconstructive and Aesthetic Surgery, Hand Surgery, Helios-Klinikum Wuppertal, University of Witten/Herdecke, Germany; bBG-University Hospital Bergmannsheil, Department of Plastic and Hand Surgery, Burn Center, Ruhr-University Bochum, Germany; cPlastic Surgery/Migraine Surgery, DRK-Hospital Berlin, Germany; and dBG-Hospital Ludwigshafen, Department of Hand-, Plastic- and Reconstructive Surgery, Burn Center, University of Heidelberg, Germany

Correspondence: olegoertz@gmx.de

Objective: Impaired microcirculation is one of the most important factors in delayed wound healing. The aim of the study was to investigate the influence of chemical and surgical interruption of sympathetic nerve fibers and α- and β-receptors blockers on muscular microcirculation. Methods: The experiment was performed on a standardized cremaster muscle model of male Wistar rats (n=51). Microcirculation was recorded via transillumination microscopy on each of the 4 test groups and in a control group before and after their r .......