ePlasty: Vol. 11
A Prospective Study of Negative Pressure Wound Therapy With Integrated Irrigation for the Treatment of Diabetic Foot Ulcers
Charles M. Zelen, DPM, FACFAS,a,b Brian Stover, DPM,a David Nielson, DPM,a,b and Muriel Cunningham, MEd

aProfessional Education and Research Institute, Roanoke, VA; bDepartment of Orthopedics, HCA Lewis-Gale Medical Center, Salem, VA

Correspondence: cmzelen@periedu.com

Objective: Patients with diabetes often present with pedal wounds resistant to standard wound healing modalities and become chronic in nature. These chronic wounds in diabetic patients have a high incidence of complications including infection and amputation. Negative pressure wound therapy has been found to facilitate healing of the stagnant pedal wound. This protocol was designed to determine wound closure rates using a unique negative pressure wound therapy system that delivers vacuum-assisted wound closure with a simultaneous irrigation feature (Svedman Wound Treatment System). Methods: A prospective single center study was conducted in adults with diabetic foot ulcers ≥cm2 or more in size showing no signs of clinical infection, and having adequate blood flow. Patients received dressing changes and irrigation on a standard regimen with weekly wound assessments for a minimum of 6 weeks. Results: 11 women and 8 men with a mean wound size of 2.4 cm × 2.2 cm were treated with the device. A tota .......