ePlasty: Vol. 14
Biological Effects of a Disposable, Canisterless Negative Pressure Wound Therapy System
Malin Malmsjö, MD, PhD,a Elizabeth Huddleston, PhD,b and Robin Martin, PhDb

aClinical Sciences, Lund, Lund University and Skåne University Hospital, Lund, Sweden; and bAdvanced Wound Management Division, Smith and Nephew Medical Ltd, Hull, UK

Correspondence: malin.malmsjo@med.lu.se
Keywords: Blood flow, dressing, wound, NPWT, vacuum

Objective: Recent developments of negative pressure wound therapy (NPWT) systems have focused on making pumps smaller, lighter, and more portable. The recently introduced PICO system manages wound fluid through a highly breathable film within the dressing, thereby negating the need for a canister, which allows greater mobility and patient concordance. The aim of this study is to compare the biological effects of this system compared to a traditional NPWT system. Methods: Laboratory tests were carried out to demonstrate the fluid handling properties of the PICO™ system. Porcine full thickness defect wounds and sutured incisional wounds were used to compare the biological effects. Wounds were treated with PICO dressings or traditional NPWT dressings and connected to either a PICO device or a traditional NPWT device. Results: The PICO dressing manages exudate predominantly through evaporative loss (up to 85% of all flu .......