ePlasty: Vol. 14
Novel Technique for Innervated Abdominal Wall Vascularized Composite Allotransplantation: A Separation of Components Approach
Devinder P. Singh, MD, Vasilios D. Mavrophilipos, BA, Jeffrey A. Zapora, MD, Jens Berli, MD, Justin Broyles, MD, Karan Chopra, MD, Jennifer Sabino, MD, Jamil Matthews, MD, E. Bryan Buckingham, MD, John S. Maddox, MD, Rachel Bluebond-Langner, MD, and Ronald P. Silverman, MD

Division of Plastic Surgery, University of Maryland School of Medicine, Baltimore, Md

Correspondence: dsingh@smail.umaryland.edu
Keywords: abdominal wall transplantation, component separation, chimerism, hernia, vascularized composite allotransplantation

Objective: Applications for Abdominal Wall Vascularized Composite Allotransplantation may expand if a functional graft with decreased immunosuppressive requirements can be designed. We hypothesize that it is anatomically feasible to prepare a functional, innervated, and vascularized abdominal composite graft using a multilayered component separation technique. Including vascularized bone in the graft design may decrease the immunosuppressive requirements by inducing immunologic c .......